Acitretin

Generic name: Acitretin
Brand names: Soriatane

Why is Acitretin prescribed?

Soriatane is prescribed for several types of severe psoriasis, a chronic skin condition that causes inflamed red patches with silvery scales. In more severe cases, the skin thickens with painful patches that fill with pus and crust over, sometimes on large portions of the body. Psoriasis can appear anywhere, but most commonly erupts on the chest and back, elbows and knees, feet and hands, scalp, and fingernails. Soriatane is used when milder forms of treatment have failed.

It's important to remember that Soriatane does not cure psoriasis; it merely helps keep it under control. Your condition may return if you stop treatment.

Most important fact about Acitretin

Soriatane must never be taken during pregnancy, as it can cause severe birth defects and physical abnormalities in a developing baby. You must not become pregnant while taking Soriatane, and you must also avoid becoming pregnant for a full 3 years after you stop taking it.

Before starting Soriatane therapy, women of childbearing age must receive birth control counseling and sign a detailed consent form stating they understand the consequences of birth control failure, the risk of birth defects, and the warning not to use alcohol (see "Special warnings about Acitretin"). You must have two negative pregnancy tests, one when you and your doctor decide on a course of Soriatane therapy and one immediately before starting treatment. You must take monthly pregnancy tests and continue to receive regular birth control counseling while using Acitretin.

In addition, you must use two forms of reliable birth control for at least 1 month prior to starting treatment, as well as for the entire time you take Soriatane and for a full 3 years after discontinuing therapy. It can take 3 years for Acitretin to be eliminated from the body.

You cannot choose progestin "mini-pill" products (such as Micronor, Nor-QD, and Ovrette) as a form of birth control because Soriatane interferes with their effectiveness. It is not yet known whether Soriatane interferes with the reliability of other hormone-based contraceptives (combination estrogen/progestin birth control pills, implants, and injections). A qualified counselor or doctor must clearly explain what kinds of birth control are effective. Women taking Soriatane who have previously taken the drug Tegison (etretinate) must continue to follow the birth control requirements for Tegison.

Your doctor can give you a referral for free birth control counseling and pregnancy testing. If you accidentally become pregnant, miss a menstrual period, or have unprotected sex while taking Soriatane, stop taking the drug and call your doctor immediately.

How should you take Acitretin?

Take Soriatane with food, exactly as prescribed by your doctor, at about the same time each day. Symptoms sometimes worsen after treatment begins, and it may take several months for your condition to improve.

--If you miss a dose...

Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular schedule. Do not take two doses at once.

--Storage instructions...

Store at room temperature, away from light and humidity, in a childproof container.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Soriatane.

More common side effects may include:
Abnormal bone growth or pain, abnormal skin changes (itching, peeling, rash, sensitivity, thinning), blood clot, changes in blood sugar or cholesterol and triglyceride (blood fat) levels, depression, eye symptoms (dryness, pain, redness, sensitivity), heart attack, joint pain, lip inflammation, liver disorders, muscle weakness, numbness or swelling of the hands or feet, inflammation of the pancreas, stroke, thoughts of suicide or self-injury, vision problems (blurring difficulty seeing at night)

Why should Acitretin not be prescribed?

Do not take Soriatane if it causes an allergic reaction or if you have ever had an allergic reaction to other drugs like it (retinoids such as Accutane and Tegison). You must also avoid Acitretin if you have kidney or liver disease, or if you have abnormally high cholesterol or triglyceride levels.

You must not take Soriatane if you are pregnant or if you plan to become pregnant within the next 3 years (see "Most important fact about Acitretin").

Soriatane must never be taken with the drugs methotrexate (Rheumatrex and Trexall) or tetracycline antibiotics (such as Achromycin V and Sumycin). The combination can cause serious, sometimes life-threatening illness.

Special warnings about Acitretin

You must not become pregnant while taking Soriatane or within 3 years of taking it (see "Most important fact about Acitretin").

Do not drink alcohol or take products containing alcohol while using Soriatane and for at least 2 months after discontinuing treatment. Combining alcohol with Acitretin causes a chemical change that makes it stay in your system longer. Read the labels on all foods and over-the-counter products to make sure they do not contain alcohol.

Soriatane causes significant changes in the level of sugar and fats in the blood. People with a history of alcoholism, diabetes, heart disease, or high levels of cholesterol or triglycerides, as well as those who are overweight, must be closely monitored when taking Soriatane.

People with degenerative spine or bone conditions must be checked regularly during treatment with Soriatane, since the drug can cause changes in their condition. Drugs like Soriatane are known to cause skeletal and bone growth problems in children. The safety and effectiveness of Soriatane have not been studied in children.

Soriatane may cause mental and behavioral changes. If you start to have symptoms of depression or aggression while taking Soriatane, or if you have thoughts of suicide or self-injury, call the doctor immediately.

Because eye conditions can worsen during Soriatane treatment, you must be carefully monitored by your doctor. The drug can cause decreased night vision and can interfere with the ability to drive or operate a vehicle safely at night. It can also interfere with the ability to wear contact lenses. Be sure to report any vision and eye problems to your doctor right away.

Soriatane increases the effects of sunlight. To prevent burning, do not stay in the sun for long periods; wear protective clothing, sunglasses, and sunscreen; and avoid using sun lamps or tanning beds. If you're being treated with phototherapy--that is, light therapy specifically used for certain skin conditions--your doctor may decrease the dosage of light while you're taking Soriatane.

Both men and women being treated with Soriatane may not give blood for at least 3 years.

Possible food and drug interactions when taking Acitretin

Do not drink alcohol or take products that contain alcohol while using Soriatane (see "Special warnings about Acitretin). Always check labels for alcohol content.

Avoid taking vitamin supplements that contain vitamin A without your doctor's approval. Soriatane is chemically related to vitamin A, and taking too much can cause harmful side effects or a toxic overdose.

If you take the herb St. John's wort, do not use hormonal estrogen/progestin pills, implants, or injections as a form of birth control. Women who take these products together can become pregnant. Make sure your doctor knows about any over-the-counter products you are taking.

If Soriatane is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Soriatane with the following:

Birth control "mini-pills" containing progestin, such as Micronor, Nor-QD, and Ovrette
Demeclocycline (Declomycin)
Doxycyline (Doryx, Vibramycin)
Etretinate (Tegison)
Methotrexate (Rheumatrex, Trexall)
Minocycline (Dynacin, Minocin)
Retinoids such as isotretinoin (Accutane) and tretinoin (Vesanoid)
Phenytoin (Dilantin)
Tetracycline (Achromycin V, Sumycin)

Special information if you are pregnant or breastfeeding

If taken during pregnancy, Soriatane can cause severe birth defects and physical abnormalities in a developing baby (see "Most important fact about Acitretin"). Do not take Soriatane if you are pregnant or plan to become pregnant within 3 years after you stop taking it.

Do not take Soriatane if you're breastfeeding, as it can harm a nursing baby.

Recommended dosage

ADULTS

The recommended dose is 25 to 50 milligrams once a day, taken with your main meal. The pharmacist who fills your prescription will also provide you with a Soriatane medication guide.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency treatment immediately.

After an overdose of Soriatane, all women of childbearing age must take a pregnancy test. They must also be counseled on the risk of birth defects and the need to use two effective forms of birth control for the next 3 years.

Symptoms of overdose may include:
Headache, vertigo (dizziness and a feeling that you or the room is spinning or moving)


Image : Acitretin

AcipHex

Generic name: Rabeprazole sodium
Brand names: AcipHex

Why is AcipHex prescribed?

AcipHex blocks acid production in the stomach. It is prescribed for the short-term (4 to 8 weeks) treatment of sores and inflammation in the upper digestive canal (esophagus). This condition, known as gastroesophageal reflux disease (GERD), is caused by the backflow of stomach acid into the esophagus over a prolonged period of time. Because GERD can be chronic, your doctor may continue to prescribe AcipHex to prevent a relapse after your initial course of treatment and to relieve symptoms of GERD such as heartburn.

AcipHex can also be prescribed for the short-term (up to 4 weeks) treatment of duodenal ulcers (ulcers that form just outside the stomach at the top of the small intestine), and for Zollinger-Ellison syndrome, a disease which causes the stomach to produce too much acid. The drug is classified as a "proton pump inhibitor." It works by blocking a specific enzyme essential to the production of stomach acid. It begins reducing acid within an hour of administration.

AcipHex is sometimes combined with the antibiotics amoxicillin and clarithromycin to treat infections caused by H. pylori, a type of bacteria that lives in the digestive tract and is often associated with recurrent ulcers.

Most important fact about AcipHex

AcipHex will work even if your symptoms are caused by a serious condition such as stomach cancer. For that reason, doctors are warned to rule out cancer whenever prescribing AcipHex.

How should you take AcipHex?

Take AcipHex once a day, with or without food. Swallow the tablet whole; it should not be crushed, chewed, or split. You can continue taking antacids during AcipHex therapy.

If you're using AcipHex along with amoxicillin and clarithromycin, take all three drugs at the same time twice a day, once in the morning and again in the evening. This three-drug regimen should be taken with meals.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.

--Storage instructions...

AcipHex should be stored at room temperature and protected from moisture.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking AcipHex. Headache is the most common side effect of AcipHex, occurring in two people out of 100.

Why should AcipHex not be prescribed?

If AcipHex gives you an allergic reaction, you will not be able to use it.

Special warnings about AcipHex

If you have stomach ulcers caused by the H. pylori bacteria, AcipHex could make the condition slightly worse. The doctor may order a test for H. pylori before prescribing AcipHex. If you test positive, the doctor may prescribe antibiotics along with AcipHex.

AcipHex has not been tested in children under 18 years of age.

Possible food and drug interactions when taking AcipHex

If AcipHex is taken with certain other drugs, the effects of either could be increase, decreased, or altered. It is especially important to check with your doctor before combining AcipHex with the following:

Cyclosporine (Neoral, Sandimmune)
Digoxin (Lanoxin)
Ketoconazole (Nizoral)
Warfarin (Coumadin)

Special information if you are pregnant or breastfeeding

The effects of AcipHex during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. The drug may appear in breast milk and should not be taken while you're breastfeeding.

Recommended dosage

ADULTS

Gastroesophageal Reflux Disease (GERD)

The usual dose is 20 milligrams once a day for 4 to 8 weeks. For patients who have not healed after 8 weeks, the doctor may prescribe an additional 8-week course of AcipHex therapy.

To Relieve Symptoms or Prevent a Relapse of GERD

The usual dose is 20 milligrams once a day.

Duodenal Ulcer

The usual dose is 20 milligrams taken once daily after the morning meal for a period of up to 4 weeks. Some people may require an additional 4 weeks of treatment.

Combination Drug Treatment to Eliminate H. Pylori

The recommended combination is 20 milligrams of AcipHex, 1,000 milligrams of amoxicillin, and 500 milligrams of clarithromycin taken twice a day for 7 days. It's important to take all three drugs for the entire 7 days. Cutting the treatment short could fail to eliminate the infection and possibly lead to antibiotic resistance.

Zollinger-Ellison Syndrome

The usual starting dose is 60 milligrams once a day, although your doctor may adjust the dose based on your individual need. Doses of up to 100 milligrams once a day or 60 milligrams twice a day are sometimes prescribed.

Overdosage

Little is known about AcipHex overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Image : AcipHex

Acetazolamide

Generic name: Acetazolamide
Brand names: Diamox

Why is Acetazolamide prescribed?

Diamox controls fluid secretion. It is used in the treatment of glaucoma (excessive pressure in the eyes), epilepsy (for both brief and unlocalized seizures), and fluid retention due to congestive heart failure or drugs. It is also used to prevent or relieve the symptoms of acute mountain sickness in climbers attempting a rapid climb and those who feel sick even though they are making a gradual climb.

Most important fact about Acetazolamide

This drug is considered to be a sulfa drug because of its chemical properties. Although rare, severe reactions have been reported with sulfa drugs. If you develop a rash, bruises, sore throat, or fever contact your doctor immediately.

How should you take Acetazolamide?

Take Acetazolamide exactly as prescribed by your doctor.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Diamox.

More common side effects may include:
Change in taste, diarrhea, increase in amount or frequency of urination, loss of appetite, nausea, ringing in the ears, tingling or pins and needles in hands or feet, vomiting

Why should Acetazolamide not be prescribed?

Your doctor will not prescribe Acetazolamide for you if your sodium or potassium levels are low, or if you have kidney or liver disease, including cirrhosis.

Diamox should not be used as a long-term treatment for the type of glaucoma called chronic noncongestive angle-closure glaucoma.

Special warnings about Acetazolamide

Be very careful about taking high doses of aspirin if you are also taking Diamox. Effects of this combination can range from loss of appetite, sluggishness, and rapid breathing to unresponsiveness; the combination can be fatal.

If you have emphysema or other breathing disorders, use Acetazolamide with caution.

If you are taking Diamox to help in rapid ascent of a mountain, you must still come down promptly if you show signs of severe mountain sickness.

Possible food and drug interactions when taking Acetazolamide

If Diamox is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Diamox with the following:

Amitriptyline (Elavil)
Amphetamines such as Dexedrine
Aspirin
Cyclosporine (Sandimmune)
Lithium (Lithonate)
Methenamine (Urex)
Oral diabetes drugs such as Micronase
Quinidine (Quinidex)

Special information if you are pregnant or breastfeeding

The effects of Diamox during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Diamox may appear in breast milk and could affect a nursing infant. If Acetazolamide is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Diamox is finished.

Recommended dosage

ADULTS

This medication is available in both oral and injectable form. Dosages are for the oral form only.

Glaucoma

This medication is used as an addition to regular glaucoma treatment. Dosages for open-angle glaucoma range from 250 milligrams to 1 gram per 24 hours in 2 or more smaller doses. Your doctor will supervise your dosage and watch the effect of Acetazolamide carefully if you are using it for glaucoma. In secondary glaucoma and before surgery in acute congestive (closed-angle) glaucoma, the usual dosage is 250 milligrams every 4 hours or, in some cases, 250 milligrams twice a day. Some people may take 500 milligrams to start, and then 125 or 250 milligrams every 4 hours. The injectable form of Acetazolamide is occasionally used in acute cases.

The usual dosage of Diamox Sequels (sustained-release capsules) is 1 capsule (500 milligrams) twice a day, usually in the morning and evening.

Your doctor may adjust the dosage, as needed.

Epilepsy

The daily dosage is 8 to 30 milligrams per 2.2 pounds of body weight in 2 or more doses. Typical dosage may range from 375 to 1,000 milligrams per day. Your doctor will adjust the dosage to suit your needs; Diamox can be used with other anticonvulsant medication.

Congestive Heart Failure

The usual starting dosage to reduce fluid retention in people with congestive heart failure is 250 milligrams to 375 milligrams per day or 5 milligrams per 2.2 pounds of body weight, taken in the morning. Diamox works best when it is taken every other day--or 2 days on, 1 day off--for this condition.

Edema Due to Medication

The usual dose is 250 milligrams to 375 milligrams daily for 1 or 2 days, alternating with a day of rest.

Acute Mountain Sickness

The usual dose is 500 milligrams to 1,000 milligrams a day in 2 or more doses, using either tablets or sustained-release capsules. Doses of Acetazolamide are often begun 1 or 2 days before attempting to reach high altitudes.

CHILDREN

The safety and effectiveness of Diamox in children have not been established. However, doses of 8 milligrams to 30 milligrams per 2.2 pounds of body weight have been used in children with various forms of epilepsy.

Overdosage

There is no specific information available on Diamox overdose, but any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Acetaminophen

Generic name: Acetaminophen
Brand names: Tylenol, Aspirin Free Anacin

Why is Acetaminophen prescribed?

Tylenol is a fever- and pain-reducing medication that is widely used to relieve simple headaches and muscle aches; the minor aches and pains associated with the common cold; backache; toothache; minor pain of arthritis; and menstrual cramps.

Most important fact about Acetaminophen

Do not use Tylenol to relieve pain for more than 10 days, or to reduce fever for more than 3 days unless your doctor has specifically told you to do so.

How should you take Acetaminophen?

Follow the dosing instructions on the label. Do not take more Tylenol than is recommended.

--If you miss a dose...

Take Acetaminophen only as needed.

--Storage instructions...

Store at room temperature. Protect extra strength gelcaps and geltabs from high humidity and excessive heat. Keep the extended relief caplets away from high heat.

What side effects may occur?

Tylenol is relatively free of side effects. Rarely, an allergic reaction may occur. If you develop any allergic symptoms such as rash, hives, swelling, or difficulty breathing, stop taking Tylenol immediately and notify your doctor.

Special warnings about Acetaminophen

Stop taking Tylenol and check with your doctor if you develop new symptoms, if redness or swelling are present, if pain gets worse or lasts more than 10 days, or if fever gets worse or lasts more than 3 days. Children's and Junior Strength Tylenol should not be used for more than 5 days for pain, or 3 days for fever.

If you generally drink 3 or more alcoholic beverages per day, check with your doctor about using Tylenol and other acetaminophen-containing products, and never take more than the recommended dosage. There is a possibility of damage to the liver when large amounts of alcohol and acetaminophen are combined.

Possible food and drug interactions when taking Acetaminophen

If Tylenol is taken with certain other drugs the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Tylenol with the following:

Alcohol
Cholestyramine (Questran)
Isoniazid (Nydrazid)
Nonsteroidal anti-inflammatory drugs such as Dolobid and Motrin
Oral Contraceptives
Phenytoin (Dilantin)
Warfarin (Coumadin)
Zidovudine (Retrovir)

Tylenol should not be used with other products containing acetaminophen.

Special information if you are pregnant or breastfeeding

As with all medications, ask your doctor or health care professional whether it is safe for you to use Tylenol while you are pregnant or breastfeeding.

Recommended dosage

ADULTS AND CHILDREN 12 YEARS AND OLDER

Tylenol Regular Strength

The usual dose is 2 tablets every 4 to 6 hours. Do not take more than 12 caplets or tablets in 24 hours.

Tylenol Extra Strength

The usual dose is 2 pills or tablespoonfuls every 4 to 6 hours. Do not take more than 8 pills or tablespoonfuls in 24 hours.

Tylenol Extended Relief

The usual dose is 2 caplets every 8 hours, not to exceed 6 caplets in any 24 hour period. Swallow each caplet whole. Do not crush, chew, or dissolve the caplets.

CHILDREN 6 TO 12 YEARS OLD

Tylenol Regular Strength

One-half to 1 tablet every 4 to 6 hours. Children in this age group should not be given more than 5 doses in 24 hours.

Junior Strength Tylenol

All doses of Junior Strength Tylenol chewable tablets may be repeated every 4 hours, up to 5 times a day. The usual dose for children 6 to 8 years of age is 2 tablets; 9 to 10 years, 2-1/2 tablets; 11 years, 3 tablets; 12 years, 4 tablets

Children's Tylenol

All doses of Children's Tylenol may be repeated every 4 hours, but not more than 5 times daily. Chewable tablets: The usual dose for children 6 to 8 years of age is 4 tablets; 9 to 10 years, 5 tablets; 11 to 12 years, 6 tablets. Suspension liquid: (A special cup for measuring dosage is provided.) The usual dose for children 6 to 8 years of age is 2 teaspoons; 9 to 10 years, 2-1/2 teaspoons; 11 to 12 years, 3 teaspoons.

CHILDREN UNDER 6 YEARS OLD

Children's Tylenol

All doses of Children's Tylenol may be repeated every 4 hours, but not more than 5 times daily. Children under 2 years old should be given Children's Tylenol only on the advice of a physician. Chewable tablets: The usual dose for children 2 to 3 years of age is 2 tablets; 4 to 5 years, 3 tablets. Suspension liquid: (A special cup for measuring dosage is provided.) The usual dose for children 4 to 11 months of age is 1/2 teaspoon; 12 to 23 months, 3/4 teaspoon; 2 to 3 years, 1 teaspoon; 4 to 5 years, 1-1/2 teaspoons.

Infants' Tylenol Concentrated Drops

The usual dose for children 0 to 3 months of age is 0.4 milliliter; 4 to 11 months, 0.8 milliliter; 12 to 23 months, 1.2 milliliters; 2 to 3 years, 1.6 milliliters.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately. Massive doses of Tylenol may cause liver damage.

Symptoms of Tylenol overdose may include:
Excessive perspiration, exhaustion, general discomfort, nausea, vomiting


Image : Acetaminophen

Acetaminophen, Oxycodone hydrochloride

Generic name: Acetaminophen, Oxycodone hydrochloride
Brand names: Endocet, Roxicet, Tylox, Percocet

Why is Acetaminophen, Oxycodone hydrochloride prescribed?

Percocet, a narcotic analgesic, is used to treat moderate to moderately severe pain. It contains two drugs--acetaminophen and oxycodone. Acetaminophen is used to reduce both pain and fever. Oxycodone, a narcotic analgesic, is used for its calming effect and for pain.

Most important fact about Acetaminophen, Oxycodone hydrochloride

Percocet contains a narcotic and, even if taken only in prescribed amounts, can cause physical and psychological dependence when taken for a long time.

How should you take Acetaminophen, Oxycodone hydrochloride?

Percocet may be taken with meals or with milk.

--If you miss a dose...

If you take Percocet on a regular schedule, take it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Percocet.

More common side effects may include:
Dizziness, light-headedness, nausea, sedation, vomiting

You may be able to alleviate some of these side effects by lying down.

Why should Acetaminophen, Oxycodone hydrochloride not be prescribed?

You should not use Percocet if you are sensitive to either acetaminophen or oxycodone.

Special warnings about Acetaminophen, Oxycodone hydrochloride

You should take Percocet cautiously and according to your doctor's instructions, as you would take any medication containing a narcotic. If you have ever had a problem with alcohol addiction, make sure your doctor is aware of it.

If you have experienced a head injury, consult your doctor before taking Percocet. The effects of Percocet may be stronger for people with head injuries, and using it may delay recovery.

If you have stomach problems, such as an ulcer, check with your doctor before taking Percocet. Percocet may hide the symptoms of stomach problems, making them difficult to diagnose and treat.

If you have ever had liver, kidney, thyroid gland, or Addison's disease (a disease of the adrenal glands), difficulty urinating, or an enlarged prostate, consult your doctor before taking Percocet.

Elderly people or those in a weakened condition should take Percocet cautiously.

This drug may impair your ability to drive a car or operate potentially dangerous machinery. Do not participate in any activities that require full alertness if you are unsure about the drug's effect on you.

Possible food and drug interactions when taking Acetaminophen, Oxycodone hydrochloride

Alcohol may increase the sedative effects of Percocet. You should not take Percocet with alcohol.

If Percocet is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Percocet with the following:

Antispasmodic drugs such as Cogentin, Bentyl, and Donnatal
Major tranquilizers such as Thorazine and Mellaril
Other narcotic painkillers such as Darvon and Demerol
Sedatives such as phenobarbital and Seconal
Tranquilizers such as Xanax and Valium

Special information if you are pregnant or breastfeeding

It is not known whether Percocet can injure a developing baby or affect a woman's reproductive capacity. Using any medication that contains a narcotic during pregnancy may cause physical addiction for your newborn baby. If you are pregnant or plan to become pregnant, inform your doctor immediately. As with other narcotic painkillers, taking Percocet shortly before delivery (especially at higher dosages) may cause some degree of impaired breathing in the mother and newborn. It is not known whether Percocet appears in breast milk, possibly harming a nursing infant. If you are breastfeeding use Percocet only under a doctor's directions.

Recommended dosage

ADULTS

The usual dose is 1 to 2 tablets of the lowest strength (2.5 milligrams oxycodone/325 milligrams acetaminophen) every 6 hours. Doctors sometimes prescribe a higher dose if necessary. The total daily dose of acetaminophen should not exceed 4 grams. The maximum daily dose recommended for each strength of Percocet (oxycodone/acetaminophen) is as follows:

2.5 milligrams/325 milligrams: 12 tablets
5 milligrams/325 milligrams: 12 tablets
7.5 milligrams/500 milligrams: 8 tablets
10 milligrams/650 milligrams: 6 tablets

CHILDREN

The safety and effectiveness of Percocet have not been established in children.

Overdosage

A severe overdose of Percocet can be fatal. If you suspect an overdose, seek medical help immediately.

Symptoms of Percocet overdose may include:
Bluish skin, eyes or skin with yellow tone, cold and clammy skin, decreased or irregular breathing (ceasing in severe overdose), extreme sleepiness progressing to stupor or coma, heart attack, low blood pressure, muscle weakness, nausea, slow heartbeat, sweating, vague bodily discomfort, vomiting


Image : Acetaminophen, Oxycodone hydrochloride

Acetaminophen, Codeine phosphate

Generic name: Acetaminophen, Codeine phosphate
Brand names: Phenaphen with Codeine, Tylenol with Codeine

Why is Acetaminophen, Codeine phosphate prescribed?

Tylenol with Codeine, a narcotic analgesic, is used to treat mild to moderately severe pain. It contains two drugs--acetaminophen and codeine. Acetaminophen, an antipyretic (fever-reducing) analgesic, is used to reduce pain and fever. Codeine, a narcotic analgesic, is used to treat pain that is moderate to severe.

People who are allergic to aspirin can take Tylenol with Codeine.

Most important fact about Acetaminophen, Codeine phosphate

Tylenol with Codeine contains a narcotic (codeine) and, even if taken in prescribed amounts, can cause physical and psychological addiction if taken for a long enough time.

Addiction may be more of a risk for a person who has been addicted to alcohol or drugs. Be sure to follow your doctor's instructions carefully when taking Tylenol with Codeine (or any other drugs that contain a narcotic).

How should you take Acetaminophen, Codeine phosphate?

Tylenol with Codeine may be taken with meals or with milk (but not with alcohol).

--If you miss a dose...

If you take Acetaminophen, Codeine phosphate on a regular schedule, take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store away from heat, light, and moisture. Keep the liquid from freezing.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Tylenol with Codeine.

More common side effects may include:
Dizziness, light-headedness, nausea, sedation, shortness of breath, vomiting

Why should Acetaminophen, Codeine phosphate not be prescribed?

You should not use Tylenol with Codeine if you are sensitive to either acetaminophen (Tylenol) or codeine.

Special warnings about Acetaminophen, Codeine phosphate

You should take Tylenol with Codeine cautiously and only according to your doctor's instructions, as you would take any medication containing a narcotic. Make sure your doctor is aware of any problems you have had with drug or alcohol addiction.

Tylenol with Codeine tablets contain a sulfite that may cause allergic reactions in some people. These reactions may include shock and severe, possibly life-threatening, asthma attacks. People with asthma are more likely to be sensitive to sulfites.

If you have experienced a head injury, consult your doctor before taking Tylenol with Codeine.

If you have stomach problems, such as an ulcer, check with your doctor before taking Tylenol with Codeine. Tylenol with Codeine may obscure the symptoms of stomach problems, making them difficult to diagnose and treat.

If you have ever had liver, kidney, thyroid, or adrenal disease, difficulty urinating, or an enlarged prostate, consult your doctor before taking Tylenol with Codeine.

If you generally drink 3 or more alcoholic beverages per day, check with your doctor before using Tylenol with Codeine and other acetaminophen-containing products, and never take more than the recommended dosage. There is a possibility of damage to the liver when large amounts of alcohol and acetaminophen are combined.

This drug may cause drowsiness and impair your ability to drive a car or operate potentially dangerous machinery. Do not participate in any activities that require full attention when using Acetaminophen, Codeine phosphate until you are sure of its effect on you.

Possible food and drug interactions when taking Acetaminophen, Codeine phosphate

Alcohol may increase the sedative effects of Tylenol with Codeine. Therefore, do not drink alcohol while you are taking Acetaminophen, Codeine phosphate.

If Tylenol with Codeine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Tylenol with Codeine with the following:

Antidepressants such as Elavil, Nardil, Parnate, and Tofranil
Drugs that control spasms, such as Cogentin
Major tranquilizers such as Clozaril and Thorazine
Other narcotic painkillers such as Darvon
Tranquilizers such as Xanax and Valium

Special information if you are pregnant or breastfeeding

It is not known if Tylenol with Codeine could injure a baby, or if it could affect a woman's reproductive capacity. Using any medication that contains a narcotic during pregnancy may cause babies to be born with a physical addiction to the narcotic. If you are pregnant or plan to become pregnant, you should not take Tylenol with Codeine unless the potential benefits clearly outweigh the possible dangers. As with other narcotic painkillers, taking Tylenol with Codeine shortly before delivery (especially at higher dosages) may cause some degree of breathing difficulty in the mother and newborn.

Some studies (but not all) have reported that codeine appears in breast milk and may affect a nursing infant. Therefore, nursing mothers should use Tylenol with Codeine only if the potential gains are greater than the potential hazards.

Recommended dosage

ADULTS

Dosage will depend on how severe your pain is and how you respond to the drug.

To Relieve Pain

A single dose may contain from 15 milligrams to 60 milligrams of codeine phosphate and from 300 to 1,000 milligrams of acetaminophen. The maximum dose in a 24-hour period should be 360 milligrams of codeine phosphate and 4,000 milligrams of acetaminophen. Your doctor will determine the amounts of codeine phosphate and acetaminophen taken in each dose. Doses may be repeated up to every 4 hours.

Single doses above 60 milligrams of codeine do not give enough pain relief to balance the increased number of side effects.

Adults may also take Tylenol with Codeine elixir (liquid). Tylenol with Codeine elixir contains 120 milligrams of acetaminophen and 12 milligrams of codeine phosphate per teaspoonful.

The usual adult dose is 1 tablespoonful every 4 hours as needed.

CHILDREN

The safety of Tylenol with Codeine elixir has not been established in children under 3 years old.

Children 3 to 6 years old may take 1 teaspoonful 3 or 4 times daily.

Children 7 to 12 years old may take 2 teaspoonsful 3 or 4 times daily.

OLDER ADULTS

Older people and anyone in a weakened or rundown condition should use Tylenol with Codeine cautiously.

Overdosage

Any medication taken in excess can cause symptoms of overdose. Severe overdosage of Tylenol with Codeine can cause death. If you suspect an overdose, seek medical attention immediately.

Symptoms of Tylenol with Codeine overdose may include:
Bluish skin, cold and clammy skin, coma due to low blood sugar, decreased, irregular, or stopped breathing, extreme sleepiness progressing to stupor or coma, general bodily discomfort, heart attack, kidney failure, liver failure, low blood pressure, muscle weakness, nausea, slow heartbeat, sweating, vomiting


Image : Acetaminophen, Codeine phosphate

Aceon

Generic name: Perindopril erbumine
Brand names: Aceon

Why is Aceon prescribed?

Aceon is used in the treatment of high blood pressure. It can be taken alone or in combination with thiazide diuretics that help rid the body of excess water. Aceon belongs to a family of drugs called angiotensin converting enzyme (ACE) inhibitors. It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Aceon also improves the flow of blood through the circulatory system.

Most important fact about Aceon

You must take Aceon regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of the drug; and you must continue taking it even if you are feeling well. Aceon does not cure blood pressure; it merely keeps it under control.

How should you take Aceon?

Aceon can be taken with or without food.

--If you miss a dose...

Take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

--Storage instructions...

Store at room temperature, protected from moisture.

What side effects may occur?

If any side effects develop, they are usually mild and are likely to disappear as therapy continues. However, if any do appear, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Aceon.

More common side effects may include:
Cough, dizziness, headache, leg pain, light-headedness, nasal inflammation, sore throat, upper respiratory infection, weakness

Why should Aceon not be prescribed?

If Aceon gives you an allergic reaction, or if you've had an allergic reaction to other ACE inhibitors, you should not take Aceon.

Special warnings about Aceon

If you develop signs of an allergic reaction (swelling of your face, lips, tongue, or throat; swollen arms and legs; difficulty swallowing or breathing) stop taking Aceon and contact your doctor immediately. You may need emergency treatment.

Contact your doctor if you develop abdominal pain with or without nausea and vomiting. ACE inhibitors such as Aceon have been known to cause intestinal swelling.

Aceon occasionally makes people dizzy, light-headed or faint, especially during the first few days of therapy. If these symptoms occur, contact your doctor. Do not drive, operate dangerous machinery, or participate in any hazardous activity that requires full mental alertness until you know how Aceon affects you. If you actually faint, stop taking the drug and call your doctor immediately.

Aceon can cause excessively low blood pressure, especially if your body is short of fluid. This problem is more likely if you are also taking a diuretic or suffer from diarrhea, vomiting, or excessive sweating. Call your doctor if you develop such signs of fluid depletion as dry mouth, weakness or fatigue, unusual thirst, restlessness or confusion, or reduced urination.

In rare instances, Aceon can damage the kidneys. When prescribing Aceon, your doctor will perform a complete assessment of your kidney function and will continue to monitor it. If you have kidney disease, the drug should be used with caution. The doctor will also take extra care if you have congestive heart failure or circulatory problems.

Aceon occasionally causes an unwanted increase in the body's potassium level. Do not use potassium supplements or salt substitutes containing potassium without your doctor's okay.

Contact your doctor promptly if you develop any sign of infection, such as a sore throat or fever. Also be sure to let the doctor know if you develop a persistent, dry cough. It could be a side effect that will disappear if the doctor switches you to another medication.

There have been rare cases of liver damage linked to Aceon. If you develop signs of liver problems such as yellowish skin and eyes, stop taking the medication and contact your doctor.

If you are receiving bee or wasp venom to prevent an allergic reaction to stings, taking Aceon at the same time may cause a severe allergic reaction. Make sure the allergist knows you are taking Aceon. In fact, before any type of procedure, notify your doctor or dentist that you are taking Aceon.

Possible food and drug interactions when taking Aceon

If Aceon is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Aceon with the following:

Cyclosporine (Neoral, Sandimmune)
Diuretics such as Aldactone, Diuril, Dyazide, Lasix, and Moduretic
Indomethacin (Indocin)
Potassium supplements such K-Lyte, K-Tab, and Slow-K
Lithium (Eskalith, Lithobid, Lithonate)
Digoxin (Lanoxin)
Gentamicin (Garamycin)

Special information if you are pregnant or breastfeeding

Aceon can cause injury or death to the developing baby when used during the last 6 months of pregnancy. Aceon should be stopped as soon as you know that you're pregnant; contact your doctor immediately.

Aceon may appear in breast milk and could affect a nursing infant. It should be used with caution if you are breastfeeding.

Recommended dosage

ADULTS

The usual starting dosage is 4 milligrams daily, taken as a single dose or divided into two smaller doses. Your doctor may increase the dosage until your blood pressure is under control, up to a maximum of 16 milligrams per day. A dose of 4 to 8 milligrams a day is usually sufficient.

If you have been taking a diuretic, your doctor may tell you to stop taking it 2 or 3 days before you start taking Aceon. If you need to continue the diuretic without interruption, the doctor may start you on Aceon at a reduced dose of 2 to 4 milligrams daily, then gradually increase the dosage if necessary.

If your blood pressure is not adequately controlled with Aceon alone, the doctor may add a diuretic to your regimen.

Aceon has not been tested in people with severe kidney disease. If you have mild kidney problems, the usual starting dosage is 2 milligrams or less per day. The dosage may be increased gradually to not more than 8 milligrams per day.

CHILDREN

Aceon has not been tested in children.

OLDER ADULTS

Higher doses (above 8 milligrams a day) are prescribed for older adults only with extra caution.

Overdosage

The most likely warning signs of an Aceon overdose are symptoms of excessively low blood pressure, including dizziness and light-headedness. If you suspect an overdose, seek medical attention immediately.

Image : Aceon

Acebutolol hydrochloride

Generic name: Acebutolol hydrochloride
Brand names: Sectral

Why is Acebutolol hydrochloride prescribed?

Sectral, a type of medication known as a beta blocker, is used in the treatment of high blood pressure and abnormal heart rhythms. When used to treat high blood pressure, it is effective used alone or in combination with other high blood pressure medications, particularly with a thiazide-type diuretic. Beta blockers decrease the force and rate of heart contractions, thus reducing pressure within the circulatory system.

Most important fact about Acebutolol hydrochloride

If you have high blood pressure, you must take Sectral regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Sectral; and you must continue taking it even if you are feeling well. Sectral does not cure high blood pressure; it merely keeps it under control.

How should you take Acebutolol hydrochloride?

Sectral can be taken with or without food. Take it exactly as prescribed, even if your symptoms have disappeared.

Try not to miss any doses. If Acebutolol hydrochloride is not taken regularly, your condition may worsen.

--If you miss a dose...

Take the forgotten dose as soon as you remember. If it's within 4 hours of your next scheduled dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

--Storage instructions...

Store at room temperature. Keep the container tightly closed. Protect from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Sectral.

More common side effects may include:
Abnormal vision, chest pain, constipation, cough, decreased sexual ability, depression, diarrhea, dizziness, fatigue, frequent urination, gas, headache, indigestion, joint pain, nasal inflammation, nausea, shortness of breath or difficulty breathing, strange dreams, swelling due to fluid retention, trouble sleeping, weakness

Why should Acebutolol hydrochloride not be prescribed?

If you have heart failure, inadequate blood supply to the circulatory system (cardiogenic shock), heart block (a type of irregular heartbeat), or a severely slow heartbeat, you should not take Acebutolol hydrochloride.

Special warnings about Acebutolol hydrochloride

If you have had severe congestive heart failure in the past, Sectral should be used with caution.

Sectral should not be stopped suddenly. This can cause increased chest pain and heart attack. Dosage should be gradually reduced.

If you suffer from asthma, seasonal allergies, other bronchial conditions, coronary artery disease, or kidney or liver disease, Acebutolol hydrochloride should be used with caution.

Ask your doctor if you should check your pulse while taking Sectral. This medication can cause your heartbeat to become too slow.

This medication may mask the symptoms of low blood sugar or alter blood sugar levels. If you are diabetic, discuss this with your doctor.

Notify your doctor or dentist that you are taking Sectral if you have a medical emergency, or before you have any surgery.

Tell your doctor if you are taking over-the-counter cold medications and nasal drops. They may interact with Sectral.

If you experience difficulty breathing, or develop hives or large areas of swelling, seek medical attention immediately. You may be having a serious allergic reaction to the medicine. Sectral can also make other severe allergies worse.

Possible food and drug interactions when taking Acebutolol hydrochloride

If Sectral is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Sectral with the following:

Albuterol (the airway-opening drug Ventolin)
Certain blood pressure medicines such as reserpine (Diupres)
Certain over-the-counter cold remedies and nasal drops such as Afrin, Neo-Synephrine, and Sudafed
Nonsteroidal anti-inflammatory drugs such as Motrin and Voltaren
Oral diabetes drugs such as Micronase

Special information if you are pregnant or breastfeeding

The effects of Sectral during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Sectral appears in breast milk and could affect a nursing infant. If Acebutolol hydrochloride is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Sectral is finished.

Recommended dosage

ADULTS

Hypertension

The usual initial dose for mild to moderate high blood pressure is 400 milligrams per day. It may be taken in a single daily dose or in 2 doses of 200 milligrams each. The usual daily dosage ranges from 200 to 800 milligrams.

People with severe high blood pressure may take up to 1,200 milligrams per day divided into 2 doses. Sectral may be taken alone or in combination with another high blood pressure medication.

Irregular heartbeat

The usual starting dosage is 400 milligrams per day divided into 2 doses. Your doctor may gradually increase the dose to 600 to 1,200 milligrams per day. If your doctor wants you to stop taking Acebutolol hydrochloride, he or she will have you taper off over a period of 2 weeks.

CHILDREN

The safety and effectiveness of Sectral have not been established in children.

OLDER ADULTS

Your doctor will determine the dosage based on your particular needs. Do not take more than 800 milligrams per day.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

There is no specific information available on Sectral; however, overdose symptoms seen with other beta blockers include:
Difficulty breathing, extremely slow heartbeat, irregular heartbeat, low blood pressure, low blood sugar, seizures, severe congestive heart failure

Accutane

Generic name: Isotretinoin
Brand names: Amnesteem, Accutane

Why is Accutane prescribed?

Accutane, a chemical cousin of vitamin A, is prescribed for the treatment of severe, disfiguring cystic acne that has not cleared up in response to milder medications such as antibiotics. It works on the oil glands within the skin, shrinking them and diminishing their output. You take Accutane by mouth every day for several months, then stop. The antiacne effect can last even after you have finished your course of medication.

Most important fact about Accutane

Because Accutane can cause severe birth defects, including mental retardation and physical malformations, a woman must not become pregnant while taking it. Before starting Accutane therapy, women of childbearing age will be asked to read a pamphlet, watch a video, and sign a detailed consent form regarding the danger of birth defects. You must have two negative pregnancy tests before beginning Accutane therapy, and must take monthly pregnancy tests while using Accutane.

In addition, you must use 2 forms of birth control during Accutane therapy, and for 1 month before and after. Each prescription for Accutane must bear a yellow qualification sticker signifying that you meet these requirements. Scientists have not ruled out the possibility that hormone-based contraceptives (birth control pills and implants) may be less reliable when taken with Accutane, so a second form of birth control should always be used while taking Accutane. If you accidentally become pregnant while taking Accutane, you should immediately consult your doctor.

How should you take Accutane?

Take Accutane two times a day with a meal, unless your doctor tells you otherwise. Swallow the capsule. Don't suck or chew it. Take it with a full glass of water, milk, or other nonalcoholic liquid. Follow your doctor's instructions carefully.

Depending on your reaction to Accutane, your doctor may need to adjust the dosage upward or downward. If you respond quickly and very well, your doctor may take you off Accutane even before the 15 or 20 weeks are up.

After you finish taking Accutane, there should be at least a 2-month "rest period" during which you are off the drug. This is because your acne may continue to get better even though you are no longer taking the medication. Once the 2 months are up, if your acne is still severe, your doctor may want to give you a second course of Accutane. If you are still growing, your doctor may recommend a longer "rest period."

Avoid consumption of alcoholic beverages.

Read the patient information leaflet available with the product.

Do not crush the capsules.

Do not share Accutane with anyone because of the risk of birth defects and other serious side effects.

--If you miss a dose...

Take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.

--Storage instructions...

Store at room temperature, away from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Accutane.

More common side effects may include:
Abnormal hair growth or loss, allergic reaction, bleeding gums, blood in urine, bowel inflammation and pain, bruising, changes in blood sugar or cholesterol levels, changes in skin pigmentation, chest pain, decreased night vision, decreased tolerance to contact lenses, delay in wound healing, depression, difficulty sleeping, dizziness, drowsiness, dry or fragile skin, dry or cracked lips, dry mouth, dry nose, fatigue, flushing, headache, hearing problems, heartbeat irregularities, herpes, inflammation or sores in the esophagus, itching, joint pain, liver disorders, menstrual changes, muscle wasting, nail disorders, nausea, nervousness, nosebleeds, peeling palms or soles, pinkeye, rash, skin infections, stomach and intestinal discomfort, stroke, sudden drop in blood pressure (causing unconsciousness), sunburn-sensitive skin, suppression of growth, sweating, swelling due to fluid retention, tendon and ligament problems, urinary discomfort, vision problems, vomiting, weakness, weight loss

Why should Accutane not be prescribed?

If Accutane gives you an allergic reaction, you will not be able to use it.

If you are a woman of childbearing age, you should not take Accutane if you are pregnant, if you think there is a possibility you might get pregnant during the treatment, or if you are unable to keep coming back to the doctor for monthly checkups, including pregnancy testing.

Special warnings about Accutane

Stop taking Accutane and notify your doctor immediately at the first sign of a skin rash or any other allergic reaction. Although they are rare, serious and even fatal allergic reactions have been known to occur.

When you first start taking Accutane, it is possible that your acne will get worse before it starts to get better.

Accutane may cause depression or other mental problems. In rare cases, it has prompted thoughts of suicide. If you begin to feel depressed or become troubled by suicidal thoughts, contact your doctor immediately.

Before starting Accutane therapy, all patients must sign a consent form noting that they are aware of the possibility of mental side effects, the danger of birth defects, and the need for certain other precautions.

If you are a woman of childbearing age and you are considering taking Accutane, you will be given both spoken and written warnings about the importance of avoiding pregnancy during the treatment. You will also be asked to sign a second consent form noting that:

You must not take Accutane if you are pregnant or may become pregnant during treatment;
If you get pregnant while taking Accutane, your baby will be at high risk for birth defects;
If you take Accutane, you must use 2 effective forms of birth control from 1 month before the start of treatment through 1 month after the end of treatment;
You must have 2 negative pregnancy tests (one just before starting Accutane therapy), and must be tested every month during therapy;
You may participate in a program that includes an initial free pregnancy test and birth control counseling session;
If you become pregnant, you must immediately stop taking Accutane and see your doctor;
You have read and understood the Accutane patient brochure and asked your doctor any questions you had;
You have been invited to participate in a survey of women being treated with Accutane.

Some people taking Accutane, including some who simultaneously took tetracycline, have experienced headache, nausea, and visual disturbances caused by increased pressure within the skull. Avoid taking tetracycline while using Accutane. See a doctor immediately if you have these symptoms; if the doctor finds swelling of the optic nerve at the back of your eye, you must stop taking Accutane at once and see a neurologist for further care.

Be careful driving at night. Some people have experienced a sudden decrease in night vision.

Accutane affects the body's processing of fats and sugars. It should be used cautiously by people with diabetes, excess weight, high triglyceride or cholesterol levels, or a tendency to drink too much alcohol. If you have any of these conditions, your doctor will monitor you closely during Accutane therapy.

You may not be able to tolerate your contact lenses during and after your therapy with Accutane.

You should stop taking Accutane immediately if you have abdominal pain, bleeding from the rectum, or severe diarrhea. You may have an inflammatory disease of the bowel.

You should not donate blood during your therapy with Accutane and for a month after you stop taking it.

You may become more sensitive to light while taking Accutane. Try to stay out of the sun as much as possible.

You should not use wax hair removal treatments or skin resurfacing procedures (dermabrasion, laser treatments) while taking Accutane or for 6 months after completing therapy.

Some people taking Accutane develop vision or hearing problems. If you notice changes in your vision or hearing, stop taking Accutane and contact your doctor.

Possible food and drug interactions when taking Accutane

While taking Accutane, do not take vitamin supplements containing vitamin A. Accutane and vitamin A are chemically related; taking them together is like taking an overdose of vitamin A.

Remember, too, that Accutane should not be combined with tetracycline antibiotics such as Doryx, Minocin, and Vibramycin.

Special information if you are pregnant or breastfeeding

Accutane causes birth defects; do not use it while pregnant. Nursing mothers should not take Accutane because of the possibility of passing the drug on to the baby via breast milk.

Recommended dosage

The recommended dosage range for Accutane is 0.5 to 1 milligram per 2.2 pounds of body weight, divided into 2 doses daily, for 15 to 20 weeks. For very severe cases, the doctor may increase the daily dose to as much as 2 milligrams per 2.2 pounds.

If after a period of 2 months or more off therapy, severe cystic acne persists, your doctor may prescribe a second course of therapy.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose of Accutane, seek medical attention immediately.

Overdosage of Accutane, like overdosage of vitamin A, can cause:
Abdominal pain, dizziness, dry or cracked lips, facial flushing, incoordination and clumsiness, headache, vomiting


Image : Accutane

Accuretic

Generic name: Quinapril hydrochloride, Hydrochlorothiazide
Brand names: Accuretic

Why is Accuretic prescribed?

Accuretic combines two types of blood pressure medication. The first, quinapril hydrochloride, is an ACE (angiotensin-converting enzyme) inhibitor. It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form (angiotensin II) that increases salt and water retention in the body and causes the blood vessels to constrict--two actions that tend to increase blood pressure.

To aid in clearing excess water from the body, Accuretic also contains hydrochlorothiazide, a diuretic that promotes production of urine. Diuretics often wash too much potassium out of the body along with the water. However, the ACE inhibitor part of Accuretic tends to keep potassium in the body, thereby canceling this unwanted effect.

Accuretic is not used for the initial treatment of high blood pressure. It is saved for later use, when a single blood pressure medication is not sufficient for the job. In addition, some doctors are using Accuretic along with other drugs to treat congestive heart failure.

Most important fact about Accuretic

You must take Accuretic regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Accuretic; and you must continue taking it even if you are feeling well. Accuretic does not cure high blood pressure; it merely keeps it under control.

How should you take Accuretic?

You can take Accuretic with or without meals.

Take Accuretic exactly as prescribed, and see your doctor regularly to make sure the drug is working properly without unwanted side effects. Do not stop taking Accuretic without first consulting your doctor.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

--Storage instructions...

Store at room temperature in a tightly closed container. Protect from moisture and light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Accuretic.

More common side effects may include:
Cough, dizziness, headache

Why should Accuretic not be prescribed?

If you are unable to urinate, avoid Accuretic.

You should not take Accuretic if you are sensitive to or have ever had an allergic reaction to any of the following: Accupril, thiazide diuretics such as HydroDIURIL and Esidrix, ACE inhibitors such as Capoten and Vasotec, or sulfa or other sulfonamide-derived drugs such as Bactrim and Septra. If you have a history of allergies, you may be at greater risk for an allergic reaction to Accuretic. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Accuretic

If you develop swelling of the face, lips, tongue or throat, or of your arms and legs, or have difficulty swallowing or breathing, stop taking the medication and contact your doctor immediately. You may need emergency treatment.

If you develop abdominal pain with or without nausea and vomiting, contact your doctor. ACE inhibitors such as Accuretic have been known to cause intestinal swelling.

You may feel light-headed, especially during the first few days of Accuretic therapy. If this occurs, notify your doctor. If you actually faint, stop taking the medication until you have consulted with your doctor.

Dehydration, excessive sweating, vomiting, or diarrhea can all deplete your body's fluids and cause your blood pressure to drop. If this leads to light-headedness or fainting, you should check with your doctor.

Inform your doctor or dentist that you are taking Accuretic before undergoing surgery or anesthesia.

Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.

If you develop any type of infection such as a sore throat or fever, contact your doctor immediately. It could indicate a more serious illness.

If you are taking Accuretic, your doctor will do a complete assessment of your kidney function and will watch it closely as long as you are taking Accuretic. If you have kidney disease, Accuretic should be used with caution.

Caution is warranted, too, if you have liver disease. If you notice a yellow tinge to your skin and the whites of your eyes, stop taking the drug and notify your doctor. This could be a sign of liver damage.

Accuretic may increase your blood sugar levels if you have diabetes. It can also trigger gout or the connective tissue disease lupus erythematosus. Use Accuretic cautiously if you have any of these problems.

The safety and effectiveness of Accuretic in children have not been established.

Possible food and drug interactions when taking Accuretic

If Accuretic is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Accuretic with the following:

Barbiturates such as phenobarbital
Cholestyramine (Questran)
Colestipol (Colestid)
Corticosteroids such as prednisone or ACTH
Diabetes medications such as insulin or Micronase
Digoxin (Lanoxin)
Diuretics such as HydroDIURIL and Lasix
Lithium (Eskalith, Lithobid)
Narcotics such as Percocet
Nonsteroidal anti-inflammatory drugs such as Naprosyn
Norepinephrine (Levophed)
Other high blood pressure medications such as Aldomet
Potassium-sparing diuretics such as Aldactone, Dyazide, and Moduretic
Potassium supplements such as Slow-K and K-Dur
Salt substitutes containing potassium
Tetracycline (Achromycin V, Sumycin)

Alcohol may increase the effect of Accuretic, and could cause dizziness or fainting. Check with your doctor before drinking alcoholic beverages.

Special information if you are pregnant or breastfeeding

ACE inhibitors such as the one in Accuretic have been shown to cause injury and even death to the unborn child when used in pregnancy during the second and third trimesters. If you are pregnant, your doctor should discontinue Accuretic as soon as possible. If you plan to become pregnant, make sure your doctor knows you are taking Accuretic. The diuretic component of Accuretic, when taken during pregnancy, can cause jaundice (yellowing of the skin and whites of the eyes) and abnormal bruising and bleeding in newborns.

Accuretic appears in breast milk and could affect a nursing infant. Because of potential harm to the baby, you'll need to choose between breastfeeding and continuing your treatment with Accuretic.

Recommended dosage

ADULTS

Accuretic is usually taken once a day. Your doctor will adjust the dosage depending on how your blood pressure responds. Daily doses of up to 80 milligrams of quinapril and 50 milligrams of hydrochlorothiazide may be prescribed, but doctors aim for the smallest dose that proves effective.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Accuretic overdose may include:
A severe drop in blood pressure, dry mouth, excessive thirst, muscle pain or cramps, nausea and vomiting, weak or irregular heartbeat, weakness and dizziness


Image : Accuretic

Accupril

Generic name: Quinapril hydrochloride
Brand names: Accupril

Why is Accupril prescribed?

Accupril is used in the treatment of high blood pressure. It can be taken alone or in combination with a thiazide type of water pill such as HydroDIURIL. Accupril is in a family of drugs known as "ACE inhibitors." It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Accupril also enhances blood flow throughout your blood vessels. Along with other drugs, Accupril is also prescribed in the treatment of congestive heart failure.

Most important fact about Accupril

You must take Accupril regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Accupril; and you must continue taking it even if you are feeling well. Accupril does not cure high blood pressure; it merely keeps it under control.

How should you take Accupril?

You can take Accupril with or without meals.

Alcohol may increase the effect of Accupril, and could cause dizziness or fainting. Avoid alcoholic beverages until you have checked with your doctor.

Take Accupril exactly as prescribed, and see your doctor regularly to make sure the drug is working properly without unwanted side effects. Do not stop taking Accupril without first consulting your doctor.

--If you miss a dose...

Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never try to "catch up" by doubling the dose.

--Storage instructions...

Accupril can be stored at room temperature. Protect from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Accupril.

More common side effects may include:
Dizziness, headache

Why should Accupril not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Accupril or similar drugs, such as Capoten and Vasotec, you should not take Accupril. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Accupril

If you develop swelling of the face, lips, tongue, or throat, or of your arms and legs, or have difficulty swallowing or breathing, you should contact your doctor immediately. You may need emergency treatment.

If you develop abdominal pain with or without nausea and vomiting, contact your doctor. ACE inhibitors such as Accupril have been known to cause intestinal swelling.

You may feel light-headed, especially during the first few days of Accupril therapy. If this occurs, notify your doctor. If you actually faint, stop taking the medication until you have consulted with your doctor.

Vomiting, diarrhea, and heavy perspiration can all deplete your body fluid; and dehydration can cause your blood pressure to drop. If this leads to light-headedness or fainting, you should check with your doctor.

Inform your doctor or dentist that you are taking Accupril before undergoing surgery or anesthesia.

Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.

If you develop a sore throat, fever, or any other sign of infection, contact your doctor immediately. It could indicate a more serious illness.

If you are taking Accupril, your doctor will do a complete assessment of your kidney function and will watch it closely as long as you are taking Accupril.

If you notice a yellow tinge to your skin and the whites of your eyes, stop taking the drug and notify your doctor immediately. This could be a sign of liver damage.

The safety and effectiveness of Accupril in children have not been established.

Possible food and drug interactions when taking Accupril

If Accupril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Accupril with the following:

Diuretics such as Lasix
Lithium (Eskalith, Lithobid)
Magnesium
Potassium-sparing diuretics such as Aldactone, Dyazide, and Moduretic
Potassium supplements such as Slow-K and K-Dur
Salt substitutes containing potassium
Tetracycline (Sumycin)

Special information if you are pregnant or breastfeeding

ACE inhibitors such as Accupril have been shown to cause injury and even death to the unborn child when used in pregnancy during the second and third trimesters. If you are pregnant, your doctor should discontinue Accupril as soon as possible. If you plan to become pregnant, make sure your doctor knows you are taking Accupril. Accupril appears in breast milk and could affect a nursing infant. If Accupril is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage

HIGH BLOOD PRESSURE

The usual starting dose is 10 or 20 milligrams taken once a day. If you have any problems with your kidneys or if you are also taking a diuretic, your starting dose may be lower. For adults over age 65, the usual starting dose is 10 milligrams. Depending on how your blood pressure responds, your doctor may increase your dose up to a total of 80 milligrams a day taken once a day or divided into two doses.

CONGESTIVE HEART FAILURE

The usual starting dose is 5 milligrams taken twice a day. Your doctor may increase the dose from week to week, up to as much as 20 to 40 milligrams daily, divided into 2 equal doses. If you have kidney problems, the dosage will be lower.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

A severe drop in blood pressure is the primary sign of an Accupril overdose.

Image : Accupril

AccuNeb

Generic name: Albuterol sulfate
Brand names: VoSpire Extended-Release Tablets, Volmax Extended-Release Tablets, Ventolin HFA, Proventil HFA, AccuNeb, Proventil

Why is AccuNeb prescribed?

Drugs containing albuterol are prescribed for the prevention and relief of bronchial spasms that narrow the airway. This especially applies to the treatment of asthma. Some brands of AccuNeb are also used for the prevention of bronchial spasm due to exercise.

Most important fact about AccuNeb

Do not take albuterol more frequently than your doctor recommends. Increasing the number of doses can be dangerous and may actually make symptoms of asthma worse.

If the dose your doctor recommends does not provide relief of your symptoms, or if your symptoms become worse, consult your doctor immediately.

How should you take AccuNeb?

If you are taking extended-release tablets, swallow them whole with some liquid--never chew or crush them.

Shake the inhalation aerosol canister well before using and make sure it's firmly seated in the plastic mouthpiece. Before using it for the first time, prime the canister with 4 sprays into the air away from your face. Prime it with 2 sprays whenever it has not been used for at least 4 days. Use only the adapter that comes with the product; do not use this adapter with any other product. Wash the plastic mouthpiece with warm running water at least once a week to prevent medication buildup and blockage.

If you are using an inhalation solution, be sure to protect it from contamination. Keep the tip of the dropper away from the lip of the bottle or any other surface. Do not use the solution if it changes color or becomes cloudy.

--If you miss a dose...

Take the forgotten dose as soon as you remember; then take any remaining doses for that day at equally spaced intervals. Never take a double dose.

--Storage instructions...

AccuNeb, Proventil syrup, and Proventil solution for inhalation can be kept in the refrigerator or at room temperature. Proventil aerosol can be stored at temperatures as low as 60 degrees Fahrenheit, but should be at room temperature before use. Protect from excessive heat.

Ventolin nebules must be used within 2 weeks of being removed from the refrigerator.

Store VoSpire tablets at room temperature in a tight, light-resistant container.

Volmax tablets should be kept refrigerated.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking albuterol.

More common side effects may include:
Aggression, agitation, allergic reaction, anxiety, back pain, chest pain or discomfort, chills and fever, coordination problems, cough, decreased appetite, depression, difficulty speaking, diabetes, diarrhea, dizziness, drowsiness, dry mouth and throat, excitement, fluid retention and swelling, flushing, general bodily discomfort, headache, heart palpitations, heartburn, hives, increased appetite, increased blood pressure, increased difficulty breathing, indigestion, irritability, labored breathing, leg cramps, light-headedness, muscle cramps, muscle spasm, nasal inflammation, nausea, nervousness, nightmares, nosebleed, overactivity, rapid heartbeat, rash, respiratory infection or disorder, restlessness, ringing in the ears, shakiness, sleeplessness, slowed movement, stomachache, stuffy nose, sweating, swelling of mouth and throat, taste sensation on inhalation, throat irritation, tooth discoloration, tremors, unusual taste, urinary problems, vomiting, weakness, wheezing

Why should AccuNeb not be prescribed?

If you are sensitive to or have ever had an allergic reaction to albuterol or other bronchodilators, you should not take AccuNeb. Make sure that your doctor is aware of any drug reactions that you have experienced.

Special warnings about AccuNeb

When taking albuterol inhalation aerosol, you should not use other inhaled medications before checking with your doctor.

Make sure the doctor is aware of it if you have a heart condition, seizure disorder, high blood pressure, abnormal heartbeat, overactive thyroid gland, or diabetes. Call your doctor immediately if you notice any change in heartbeat or pulse while taking AccuNeb.

You may have an immediate, serious allergic reaction to the first dose of albuterol, causing symptoms such as hives, rash, and swelling of the mouth, throat, lips, and tongue. The drug has been known to cause life-threatening bronchial spasms, especially with the first dose from a new canister or vial. There have also been rare reports of skin reddening and peeling in children taking albuterol syrup.

Do not exceed your doctor's recommended dose of albuterol. If you need more than usual, check with your doctor. Your asthma may be getting unstable, and you may need another medication. Do not, however, change your medication without first consulting your doctor or pharmacist.

Possible food and drug interactions when taking AccuNeb

Use albuterol inhalation aerosol with other aerosol bronchodilators only if your doctor recommends it.

If albuterol is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining albuterol with the following:

Antidepressants classified as MAO inhibitors, such as Nardil and Parnate, and tricyclic antidepressants such as Elavil, Norpramin, Pamelor, and Tofranil.
Beta blockers (heart and blood pressure drugs such as Inderal, Tenormin, and Sectral)
Digoxin (Lanoxin)
Drugs similar to albuterol, such as Alupent, Brethine, Isuprel, and epinephrine
Drugs that lower potassium levels (water pills such as Lasix or HydroDIURIL)

Special information if you are pregnant or breastfeeding

The effects of albuterol during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether albuterol appears in breast milk. If AccuNeb is essential to your health, your doctor may advise you to stop nursing your baby until your treatment is finished.

Recommended dosage

ADULTS

Inhalation Aerosol

If you are being treated for a sudden or severe bronchial spasm or the prevention of asthma symptoms, the usual dosage of albuterol inhalation aerosol is 2 inhalations repeated every 4 to 6 hours. More frequent use is not recommended. In some individuals, 1 inhalation every 4 hours may be sufficient.

To prevent exercise-induced bronchial spasm, the usual dosage is 2 inhalations, 15 minutes prior to exercise.

Tablets

The usual starting dose for adults and children 12 years of age and older is 2 or 4 milligrams 3 to 4 times a day. Dosage should not exceed 32 milligrams per day.

Syrup

The usual starting dose for adults and children over 12 years of age is 1 or 2 teaspoonfuls 3 or 4 times a day. Dosage should not exceed 4 teaspoonfuls 4 times a day.

Proventil Inhalation Solution

The usual dosage for adults and children 12 years of age and older is 2.5 milligrams administered 3 to 4 times daily by nebulization. Do not use more often or in higher doses. To administer 2.5 milligrams, use the entire contents of a unit-dose bottle of the 0.083% solution or dilute 0.5 milliliter of the 0.5 percent solution with 2.5 milliliters of sterile normal saline solution.

Proventil Repetabs, Volmax Extended-Release Tablets, and VoSpire Extended-Release Tablets

The usual recommended dosage for adults and children 12 years of age and older is 8 milligrams every 12 hours. In some people, 4 milligrams every 12 hours may be sufficient. If the desired effect is not achieved with the standard dosage, your doctor may increase doses to a maximum of 32 milligrams per day, divided into two 16-milligram doses spaced 12 hours apart. Those taking standard tablets or syrup can switch to extended-release tablets. One extended-release tablet every 12 hours is equivalent to one 2-milligram standard tablet every 6 hours.

CHILDREN

Inhalation Aerosol

The usual dose of albuterol inhalation aerosol for children aged 4 and over (12 and over for Proventil) is 2 inhalations every 4 to 6 hours. To prevent exercise-induced bronchial spasm, the dose is 2 inhalations 15 minutes prior to exercise.

Tablets

The usual starting dose for children 6 to 12 years of age is 2 milligrams 3 or 4 times a day. The dose can be increased with caution but should not exceed 24 milligrams per day. Safety and effectiveness in children under 6 have not been established.

Syrup

The usual starting dose for children 6 to 12 years of age is 1 teaspoonful 3 to 4 times a day. The dosage should not exceed 3 teaspoonfuls 4 times a day. For children 2 to 6 years of age, the starting dose is 0.1 milligram per 2.2 pounds of body weight, to a maximum of 4 milligrams, 3 times a day.

Proventil Repetabs, Volmax Extended-Release Tablets, and VoSpire Extended-Release Tablets

The usual starting dosage for children 6 to 12 years of age is 4 milligrams every 12 hours. The dosage can be increased with caution but should not exceed 24 milligrams per day.

AccuNeb Inhalation Solution

The usual starting dose for children 2 to 12 years of age is 0.63 or 1.25 milligrams 3 or 4 time daily by nebulization. To administer, use the entire contents of the prescribed unit-dose vial. The 1.25 milligram dosage may be more helpful for children 6 to 12 with more severe asthma, and for children 11 to 12.

OLDER ADULTS

Oral Dosage

The usual starting dose of tablets or syrup is 2 milligrams 3 or 4 times a day. If needed, the dosage may be increased gradually to as much as 8 milligrams 3 or 4 times a day.

Overdosage

Symptoms of albuterol overdose may include:
Dizziness, dry mouth, fatigue, general feeling of illness, headache, high or low blood pressure, insomnia, nausea, nervousness, radiating chest pain, rapid or irregular heartbeat, seizures, tremors

Heart attack and even death have been associated with abuse of albuterol inhalation. Exaggerated side effects may also be a sign of an overdose. If you suspect an overdose, seek medical attention immediately.

Accolate

Generic name: Zafirlukast
Brand names: Accolate

Why is Accolate prescribed?

Accolate helps prevent asthma attacks. It is prescribed for long-term treatment.

Most important fact about Accolate

Accolate will not stop an asthma attack once it starts. You will still need to use an airway-opening medication when an attack occurs.

How should you take Accolate?

Accolate should be taken twice every day, whether or not you have had any recent asthma attacks. Do not take the medication with food. Allow at least 1 hour to pass before eating, or wait for 2 hours after a meal. You can continue to take Accolate while using another medication to stop an attack.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature in a dark, dry place.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Accolate.

More common side effects may include:
Headache, infection, nausea

Why should Accolate not be prescribed?

If you have had an allergic reaction to Accolate or to any of its ingredients, avoid Accolate.

Special warnings about Accolate

While taking Accolate, you should not stop--or even cut down on--any other asthma medication you are using unless your doctor recommends it. Remember that Accolate is not an airway-opening medication. You will still need an inhaler to stop an attack.

If you have been taking an oral steroid drug and your doctor does decide to cut back the dosage, there is a remote chance that complications will follow. Inform your doctor of any new symptoms.

Also call your doctor if you develop any of the following: pain in the upper right abdomen, nausea, fatigue, lethargy, loss of appetite, itching, flu-like symptoms, or jaundice (yellowing of the skin and eyes). These are signs of a liver problem--a rare side effect of Accolate that tends to develop more often in women. If tests show the problem to be serious, you'll have to stop using the drug. The symptoms will disappear once you stop.

Possible food and drug interactions when taking Accolate

A full stomach can reduce Accolate's effectiveness. Do not take with meals.

If Accolate is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Accolate with the following:

Aspirin (Ecotrin, Genuine Bayer, others)
Astemizole (Hismanal)
Blood-thinning drugs such as Coumadin
Carbamazepine (Tegretol)
Cyclosporine (Sandimmune, Neoral)
Erythromycin (E.E.S., E-Mycin, others)
Heart and blood pressure medications called calcium channel blockers, including Calan, Cardizem, and Procardia
Phenytoin (Dilantin)
Terfenadine (Seldane)
Theophylline (Theo-Dur, others)
Tolbutamide (Orinase)

Special information if you are pregnant or breastfeeding

Accolate should be taken during pregnancy only if clearly needed. If you are pregnant or plan to become pregnant, inform your doctor immediately.

Accolate does find its way into breast milk and should not be taken by nursing mothers.

Recommended dosage

ADULTS

The usual dose for adults and children 12 years of age and over is 20 milligrams twice a day.

CHILDREN

The usual dose for children 5 to 11 years of age is 10 milligrams twice a day. Safety and effectiveness in children under 5 years of age have not been established.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Accolate overdose may include:
Rash, upset stomach